Thank you for visiting our research page. We are a computational group at Tufts University working on Ecology and Evolution and Global Change Biology.
Our research asks "when is evolution important for explaining species' persistence, and
why?" It's now clear that rapid climate change, habitat loss, disease spillover, and changing species interactions have driven
many species to very low population abundance or extinction. And it's also clear that species can sometimes adapt rapidly to changing conditions,
but we still know relatively little about the ecological, evolutionary, and genetic factors that facilitate or prohibit rapid adaptation.
We combine theoretical population genetic models, genomic data, and observational ecological data to learn how population dynamics and adaptation
are shaped by environmental change.
In addition to our research, we seek to enact positive change in our scientific and local communities, especially in terms of representation in
science. We aim to be an explicitly anti-racist lab, and we welcome scholars of all ancestries, genders, disability statuses, and sexualities.
The lab's anti-racism statement can be found here, and you can read more about our vision for DEI work in my application materials
Tufts undergraduates are more than welcome to contact us about research opportunities. At the moment opportunities are a bit limited, but we reasssess availability each semester as students
graduate or positions open. Please fill out this form and we will get back to you if a position opens. For information about joining the lab, please visit the people page.
- July 2023: Alejandro Calderon presented his work on adaptation rates in multivoltine insects at SISG at the Univsersity of Washington. Congrats Alejandro!
- July 2023 Kasturi Lele presented her work on community assembly of microbes found in sourdough starters. Congrats Kasturi!
- June 2023: Congratulations to Kasturi Lele, who passed her qualifying exam today! Her projects address microbial community assembly dynamics using both modeling and experiments.
- May 2023: Our preprint on phylogenomics and interspecific competition is out! Congrats to Wolfe Lab PhD student Nicolas Louw, who led this project.
- Janurary 2023: A new paper is out in Ecology. We examine the dynamics of pathogen transmission when pathogens can be spread by multiple distinct mechanisms, with
applications to population declines in apline carnations. Many thanks to co-authors Janis Anotovics, Mike Boots, Emme Bruns, and Michael Hood!
- Janurary 2023: Lawrence and SJ attended the AmNat conference at Asilomar State Beach, where we presented some preliminary results about the evolutionary dynamics of costly disease
resistance alleles. You can find SJ's poster here. Congrats SJ on a successful first conference!
- August 2022: Undergraduates Alison Leav and Daphne Garcia completed summer projects in the lab, focusing on pigeon adaptation to climate change
and the evolutionary processes underlying genomic vulnerability. Thanks for making this such a stimulating summer!
- July 2022: We received a Springboard Award
to work collaboratively with Julia Gouvea,
which will help us to further develop our work on the navigation of scientific identities in computational biology classrooms. This work is led by our incredible
colleague Sugat Dabholkar.
- April 2022: Undergraduate Daphne Garcia will join the lab to study genomic vulnerability using model-based simulations. Daphne received a Tufts Summer Fellowship. Welcome Daphne!
- January 2022: New paper out in Trends in Parasitology, led by Emily Ebel. Dr. Ebel evaluates the malaria hypothesis using
modern GWAS summary statistic data for severe malaria incidence. The paper can be found here, unfortunately it is behind a paywall but you can email us for a copy.
- December 2021: We had our first official lab event! A small outing to Boston to visit a holiday market. Photo credit to SJ McGeady.
- October 2021: Welcome to Adam Pepi, the lab's first postdoc! Adam joins us from UC Davis, where he completed his PhD in entomology. Adam is a population ecologist whose
work combines field studies and mathematical modeling. He researches the role of climate and infectious disease in shaping species population dynamics. At Tufts he will combine
genomic data from butterflies with population modeling to study how climate may jointly shape local adaptation and population dynamics. Welcome Dr. Pepi, we are so lucky to have
- September 2021: The lab welcomes three rotating graduate students: SJ McGeady, Kasturi Lele, and Alejandro Calderon! The students are working on a mixture of theoretical and
computational topics, including the eco-evolutionary determinants of disease-related adaptation, the role of rare variants in evolutionary processes, and mediators of coexistence
in microbial communities.
- August 2020: We are recruiting PhD students for the fall 2021 cohort in Biology at Tufts, please click here for more info! The application deadline is December 1, 2020.